BONTAC | Briefly introduce what nad powder is

BONTAC | Briefly introduce what nad powder is

NAD (Nicotinamide Adenine Dinucleotide) is a coenzyme composed of two nucleotides, composed of adenine and nicotinamide, which plays a key role in cellular energy metabolism. NAD generates ATP from metabolic reactions by passing electrons in the electron transport chain in the mitochondria. It also plays a role in regulating DNA repair, gene expression and cell signaling. NAD, an important molecule for cell survival and function, decreases with age, leading to impairment of these processes. NAD+ supplements are being studied for their possible anti-aging benefits and ability to improve cellular function.
Get A Quote

Advantages of NMNH

NMNH: 1. “Bonzyme” Whole-enzymatic method, environmental-friendly, no harmful solvent residues manufacturing powder. 2. Bontac is a very first manufacture in the world to produce the NMNH powder on the level of high purity, stability. 3. Exclusive “Bonpure” seven-step purification technology, high purity(up to 99%) and stability of production of NMNH powder 4. Self-owned factories and obtained a number of international certifications to ensure high quality and stable supply of products of NMNH powder 5. Provide one-stop product solution customization service

Advantages of NADH

NADH: 1. Bonzyme whole-enzymatic method, environmental-friendly, no harmful solvent residues 2. Exclusive Bonpure seven-step purification technology, purity up higher than 98 % 3. Special patented process crystal form, higher stability 4. Obtained a number of international certifications to ensure high quality 5. 8 domestic and foreign NADH patents, leading the industry 6. Provide one-stop product solution customization service

Advantages of NAD

NAD:  1. “Bonzyme” Whole-enzymatic method, environmental-friendly, no harmful solvent residues 2. Stable supplier of 1000+ enterprises around the world 3. Unique “Bonpure” seven-step purification technology, higher product content and higher conversion rate 4. Freeze drying technology to ensure stable product quality 5. Unique crystal technology, higher product solubility 6. Self-owned factories and obtained a number of international certifications to ensure high quality and stable supply of products

Advantages of MNM

NMN:  1. “Bonzyme”Whole-enzymatic method, environmental-friendly, no harmful solvent residues 2. Exclusive“Bonpure”seven-step purification technology, high purity(up to 99.9%) and stability 3. Industrial leading technology: 15 domestic and international NMN patents 4. Self-owned factories and obtained a number of international certifications to ensure high quality and stable supply of products 5. Multiple in vivo studies show that Bontac NMN is safe and effective 6. Provide one-stop product solution customization service 7. NMN raw material supplier of famous David Sinclair team of Harvard University

about us

We Have The Best Solutions for Your Business

Bontac Bio-Engineering (Shenzhen) Co., Ltd. (hereafter referred to as BONTAC) is a high-tech enterprise established in July 2012. BONTAC integrates R&D, production and sales, with enzyme catalysis technology as the core and coenzyme and natural products as main products. There are six major series of products in BONTAC, involving coenzymes, natural products, sugar substitutes, cosmetics, dietary supplements and medical intermediates.

As the leader of the global NMN industry, BONTAC has the first whole-enzyme catalysis technology in China. Our coenzyme products are widely used in health industry, medical & beauty, green agriculture, biomedicine and other fields. BONTAC adheres to independent innovation, with more than 170 invention patents. Different from the traditional chemical synthesis and fermentation industry, BONTAC has advantages of green low-carbon and high-value-added biosynthesis technology. What’s more, BONTAC has established the first coenzyme engineering technology research center at the provincial level in China which also is the sole in Guangdong Province.

In the future, BONTAC will focus on its advantages of green, low-carbon and high-value-added biosynthesis technology, and build ecological relationship with academia as well as upstream/downstream partners, continuously leading the synthetic biological industry and creating a better life for human beings.

Learn More

NAD powder manufacturing method

The preparation methods of NAD powder are mainly divided into chemical synthesis method and biocatalytic method, among which biocatalytic method includes biological fermentation method and enzyme catalysis method. Enzyme catalysis method has gradually become the mainstream direction because of its advantages of green, environmental protection and pollution-free. And then the purity of NAD powder will reach 99% after the procedure of further purifying. 

NAD powder manufacturing method

NAD powder efficacy in health

Molecules that can be taken in supplement form to increase NAD levels in the body are referred to by some as “NAD boosters.” Studies conducted over the past six decades suggest that the following are some of the many benefits associated with taking an NAD supplement:
Can Help Restore Mitochondrial Function
Helps Repair Blood Vessels —A 2018 mice study found that supplementation could aid in repair and growth of aged blood vessels. There’s also some evidence it can help manage heart disease risk factors like high blood pressure and high cholesterol.
May Improve Muscle Function — One animal study conducted in 2016 found that degenerative muscles had improved muscle function when supplemented with NAD+ precursors.
Potentially Helps Repair Cells and Damaged DNA — Some studies have found evidence that NAD+ precursor supplementation leads to an increase in DNA damage repair. NAD+ is broken down into two component parts, nicotinamide and ADP-ribose, which combine with proteins to repair cells.
May Help Improve Cognitive Function — Several studies conducted on mice have found that mice treated with NAD+ precursors experienced improvements in cognitive function, learning and memory. Findings have led researchers to believe that NAD supplement may help protect against cognitive decline/Alzheimer’s disease.
May Help Prevent Age-Related Weight Gain — A 2012 study showed that when mice fed a high-fat diet were given an NAD supplement, they gained 60 percent less weight than they did on the same diets without the supplement. One reason this may be true is that nicotinamide adenine dinucleotide helps regulate production of stress- and appetite-related hormones, thanks to its effects on circadian rhythms.
Precursors are molecules used in chemical reactions inside the body to create other compounds. There are a number of precursors of NAD+ that result in higher levels when you consume enough of them.

NAD powder efficacy in health

BONTAC NAD product features and advantages

1、Enzymatic method, environmental-friendly, no harmful solvent residues manufacturing powder 
2、High purity(up to 99%) and stability of production of NAD powder 
3、Self-owned factories and obtained a number of international certifications to ensure high quality and stable supply of products of NAD powder  
4、Multiple in vivo studies show that Bontac NAD powder is safe and effective
5、Provide one-stop product solution customization service

BONTAC NAD product features and advantages
User Reviews

What users say about BONTAC

BONTAC is a reliable partner that we have been working with for many years. The purity of their coenzyme is very high. Their COA can achieve relatively high test results.

Front

I discovered BONTAC in 2014 because David's article in cell about NAD and NMN related showed that he used BONTAC's NMN for his experimental material. Then we found them in China. After so many years of cooperation, I think it is a very good company.

Hanks

I think green, healthy and high purity are the advantages of BONTAC's products compared with others. I still work with them to this day.

Phillip

In 2017, we chose BONTAC's coenzyme, during which our team encountered many technical problems and consulted their technical team, which were able to give us good solutions. Their products are shipped very fast and they work more efficiently.

Gobbs
Frequently Asked Question

Do you have any question?

Nicotinamide adenine dinucleotide (NAD) has several essential roles in metabolism. It acts as a coenzyme in redox reactions, as a donor of ADP-ribose moieties in ADP-ribosylation reactions, as a precursor of the second messenger molecule cyclic ADP-ribose, as well as acting as a substrate for bacterial DNA ligases and a group of enzymes called sirtuins that use NAD+ to remove acetyl groups from proteins. In addition to these metabolic functions, NAD+ emerges as an adenine nucleotide that can be released from cells spontaneously and by regulated mechanisms, and can therefore have important extracellular roles.

First, inspect the factory. After some screening, NAD companied that directly face consumers pay more attention to brand building. Therefore, for a good brand, quality is the most important thing, and the first thing to control the quality of raw materials is to inspect the factory. Bontac company actually manufacturing NAD powder of high quality with the caterias of SGS. Secondly, the purity is tested. Purity is one of the most important parameters of NAD powder. If high purity NAD cannot be guaranteed, the remaining substances are likely to exceed the relevant standards. As the attached certificates demonstrates that the NAD powder produced by Bontac reach the purity of 99.9%. Finally, a professional test spectrum is needed to prove it. Common methods for determining the structure of an organic compound include Nuclear Magnetic Resonance Spectroscopy (NMR) and high-resolution mass spectrometry (HRMS). Usually through the analysis of these two spectra, the structure of the compound can be preliminarily determined.

The difference all comes down to the charge of these coenzymes. NAD+ is written with a superscript + sign because of the positive charge on one of its nitrogen atoms. It is the oxidized form of NAD. It’s considered “an oxidizing agent” because it accepts electrons from other molecules.
Although they are different chemically, these terms are mostly used interchangeably when discussing their health benefits. Another term you may come across is NADH, which stands for nicotinamide adenine dinucleotide (NAD) + hydrogen (H). This is also used interchangeably with NAD+ for the most part. Both are nicotinamide adenine dinucleotides that function as either hydride donors or hydride acceptors. The difference between these two is that that NADH becomes NAD+ after it donates an electron to another molecule.

Our updates and blog posts

The Immuno-Enhancing Effect of Rh2-L on Double Emulsion Adjuvant Against Foot-and-Mouth Disease

1. Introduction At present, vaccine is the preferred option for the prevention of foot-and-mouth disease (FMD), for which the adjuvant is essential due to its strong role in boosting immune response associated with vaccine antigens. Herein, Rh2 liposomes (Rh2-L) are prepared by ethano injection methods, then loaded into a double emulsion adjuvant and emulsified into a Water-in-Oil-in-Water (W/O/W) emulsion, together with FMDV antigen, for the prevention of FMD. 2. About FMD FMD, also known as aphthous fever, is a viral and fulminating infectious disease in which the foot-and-mouth disease virus (FMDV) violates hoofed livestock such as cattle, pigs and sheep. Since FMD is a zoonotic disease with high incidence and fast transmission speed, FMD vaccination is significant for those with long-term contact with livestock or low immunity such as the herders, veterinarians and children. 3.The significance of transform Rh2 into Rh2-L By transformation of Rh2 into Rh2-L, on the one hand, the poor solubility and hemolysis of Rh2 can be mitigated to a large extent. On the other hand, Rh2-L functions as a liposome. Noteworthily, liposome itself has been revealed to be an adjuvant in vaccine design to improve immune response by interacting with antigen-presenting cells (APCs), increasing the representation of immune stimulants to APCs, and stimulating innate immunity. 4. The immune-enhancing effect of Rh2-L on FMD vaccine Rh2-L has a immune-enhancing effect, as evidenced by an increase in humoral and cellular immune responses. In the FMDV model, the group of the FMD vaccine prepared with double emulsion adjuvants containing Rh2-L presents a more desirable protective effect relative to other groups. This group has a higher neutralizing antibody titer, stronger lymphocyte proliferation responses, and higher levels of cellular and humoral immune cytokine production, including IFN-γ and IL-4. 5. Conclusion Rh2-L can further boost the immune effect of the double emulsion adjuvant against foot-and-mouth disease, which may be a promising and powerful platform for subunit vaccine adjuvant. 6. Reference Saiya Miao, Qiufang Jing, Xuanyu Wang, et al. “Immuno-Enhancing Effect of Ginsenoside Rh2 Liposomes on Foot-and-Mouth Disease Vaccine”. Molecular Pharmaceutics. 2024 21 (1), 183-193. DOI: 10.1021/acs.molpharmaceut.3c00733 BONTAC advantages BONTAC is ·the first enterprise in China to provide mass production of ginsenosides (Rh2) by enzymatic synthesis. BONTAC has unique Bonzyme enzymatic synthesis technology. Our coenzyme products are widely used in health industry, medical & beauty, green agriculture, biomedicine and other fields. BONTAC has more than 160 invention patents, with strict third-party self-inspection. Both the high-quality product and excellent service can be better ensured here. BONTAC has 12 years of industry experience, which is worthy of your trust.  Disclaimer This article is based on the reference in the academic journal. The relevant information is provide for sharing and learning purposes only, and does not represent any medical advice purposes. If there is any infringement, please contact the author for deletion. The views expressed in this article do not represent the position of BONTAC.  Under no circumstances will BONTAC be held responsible or liable in any way for any claims, damages, losses, expenses, costs or liabilities whatsoever (including, without limitation, any direct or indirect damages for loss of profits, business interruption or loss of information) resulting or arising directly or indirectly from your reliance on the information and material on this website.

Elevating Wellness: BONTAC's NMN Powder Offerings

Elevating Wellness: BONTAC's NMN Powder Offerings As we delve into the realm of health and wellness, the spotlight shines brightly on NMN powder, a powerful supplement embraced by many for its potential benefits. At BONTAC, we take pride in offering a premium selection of NMN powder formulations designed to support optimal health and vitality. Our commitment to excellence shines through in our dedication to scientific innovation, top-notch technical support, and unwavering focus on quality. Join us on a journey to explore the transformative effects of BONTAC's NMN powder offerings. Exploring BONTAC's NMN Powder Selection   BONTAC's NMN powder selection stands out as a cornerstone of our commitment to promoting wellness. We meticulously source and formulate our NMN powder to ensure the highest purity and efficacy, setting a gold standard in the industry. With a focus on quality and potency, BONTAC's NMN powder are designed to support cellular health, energy production, and overall well-being. Whether you require cutting-edge laboratory equipment, innovative research tools, or transformative bio-based materials, BONTAC has you covered. Our extensive product portfolio spans a wide spectrum, including but not limited to genetic engineering tools, biomaterials, diagnostic assays, regenerative medicine solutions, and environmental sustainability innovations. By providing access to these advanced biotechnology products, we empower businesses to stay ahead of the curve and drive progress in their respective fields. Features and Purity of BONTAC's NMN Powder   The hallmark of BONTAC's NMN powder offerings lies in their exceptional quality and purity standards. Our products undergo rigorous testing and quality control measures to guarantee maximum effectiveness and safety. Customers trust in the purity and authenticity of BONTAC's NMN powder, knowing that they are investing in products that deliver tangible results and contribute to their wellness journey. Leveraging BONTAC's NMN Powder for Optimal Health   Integrating BONTAC's NMN powder into your daily wellness regimen opens doors to a world of health benefits. Our team is dedicated to providing unparalleled technical support and expertise to guide you through the supplementation process. Partnering with BONTAC ensures that you have access to premium NMN formulations backed by scientific research and innovation, empowering you to achieve your health goals with confidence. Conclusion In conclusion, BONTAC's NMN powder offerings represent a commitment to holistic wellness and vitality. With a focus on excellent products, technical innovation, and unwavering customer support, we stand as your trusted partner in the journey toward optimal health. Embrace the power of BONTAC's premium NMN powder and elevate your well-being to new heights.

Elevating Wellness: BONTAC Advanced Raw Materials for Cellular Health Supplements

Elevating Wellness: BONTAC Advanced Raw Materials for Cellular Health Supplements In today's fast-paced world, the quest for optimal health and wellness has led to a surge in the demand for high-quality cellular health supplements. At BONTAC, we specialize in crafting advanced raw materials that cater to the intricate needs of cellular health, promoting vitality and resilience at the core level of the body. Cutting-Edge Formulations for Cellular Health   At BONTAC, our team of experts dedicates itself to pushing the boundaries of cellular nourishment through innovative approaches and meticulous formula development processes. Our advanced formulations are designed to enhance cellular function, supporting overall well-being and longevity through targeted nutritional support. At BONTAC, we recognize that every person's metabolism-boosting journey is unique, and we strive to provide a diverse range of products that cater to a wide spectrum of needs and preferences. Whether it's supporting energy production, promoting efficient nutrient utilization, or enhancing metabolism-boosting flexibility, our comprehensive lineup of metabolism-boosting products is designed to empower individuals to take control of their metabolism-boosting well-being. Unlocking the Benefits of Cellular Health Supplements   BONTAC raw materials for cellular health supplements are carefully crafted to strengthen cellular resilience, boost energy metabolism, and promote optimal cell function. By incorporating the latest scientific advancements, our products can fortify the body at the cellular level, offering a comprehensive approach to enhancing health and vitality. Partnering with BONTAC for Cellular Wellness Solutions   When businesses partner with BONTAC, they gain access to tailored strategies for cellular health, backed by our expertise in the field. Our commitment to technical innovation ensures that our products continually evolve to meet the changing needs of our customers. Through collaboration with BONTAC, businesses can tap into our comprehensive business coverage and strengthen their health offerings with our advanced cellular health supplements. By choosing BONTAC's metabolism-boosting products, you are not only investing in your health but also aligning yourself with a company that is dedicated to advancing the field of metabolism-boosting science. With our unwavering commitment to quality, innovation, and customer satisfaction, we invite you to join us on this transformative journey towards optimal metabolism-boosting health and a vibrant, fulfilling life. Conclusion   Embark on a transformative journey towards enhanced health and longevity with BONTAC state-of-the-art raw materials for cellular health supplements. Our commitment to excellence, technical support, and innovation sets us apart in the industry, ensuring that our products meet or even exceed the expectations of our partners and customers. Join us in optimizing cellular wellness and unlocking the full potential of health with BONTAC by your side. In conclusion, BONTAC advanced raw materials for cellular health supplements demonstrate our dedication to providing outstanding products that prioritize the well-being of our customers. If you require further information or assistance, please do not hesitate to reach out to our team.

Get In Touch

Don't hesitate to contact with us

Sending your message. Please wait...