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Why Choose BONTAC?
Advantages of NMNH
NMNH: 1. “Bonzyme” Whole-enzymatic method, environmental-friendly, no harmful solvent residues manufacturing powder. 2. Bontac is a very first manufacture in the world to produce the NMNH powder on the level of high purity, stability. 3. Exclusive “Bonpure” seven-step purification technology, high purity（up to 99%) and stability of production of NMNH powder 4. Self-owned factories and obtained a number of international certifications to ensure high quality and stable supply of products of NMNH powder 5. Provide one-stop product solution customization service
Advantages of NADH
NADH: 1. Bonzyme whole-enzymatic method, environmental-friendly, no harmful solvent residues 2. Exclusive Bonpure seven-step purification technology, purity up higher than 98 % 3. Special patented process crystal form, higher stability 4. Obtained a number of international certifications to ensure high quality 5. 8 domestic and foreign NADH patents, leading the industry 6. Provide one-stop product solution customization service
Advantages of NAD
NAD: 1. “Bonzyme” Whole-enzymatic method, environmental-friendly, no harmful solvent residues 2. Stable supplier of 1000+ enterprises around the world 3. Unique “Bonpure” seven-step purification technology, higher product content and higher conversion rate 4. Freeze drying technology to ensure stable product quality 5. Unique crystal technology, higher product solubility 6. Self-owned factories and obtained a number of international certifications to ensure high quality and stable supply of products
Advantages of MNM
NMN: 1. “Bonzyme”Whole-enzymatic method, environmental-friendly, no harmful solvent residues 2. Exclusive“Bonpure”seven-step purification technology, high purity（up to 99.9%) and stability 3. Industrial leading technology: 15 domestic and international NMN patents 4. Self-owned factories and obtained a number of international certifications to ensure high quality and stable supply of products 5. Multiple in vivo studies show that Bontac NMN is safe and effective 6. Provide one-stop product solution customization service 7. NMN raw material supplier of famous David Sinclair team of Harvard University
We Have The Best Solutions for Your Business
Bontac Bio-Engineering (Shenzhen) Co., Ltd. (hereafter referred to as BONTAC) is a high-tech enterprise established in July 2012. BONTAC integrates R&D, production and sales, with enzyme catalysis technology as the core and coenzyme and natural products as main products. There are six major series of products in BONTAC, involving coenzymes, natural products, sugar substitutes, cosmetics, dietary supplements and medical intermediates.
As the leader of the global NMN industry, BONTAC has the first whole-enzyme catalysis technology in China. Our coenzyme products are widely used in health industry, medical & beauty, green agriculture, biomedicine and other fields. BONTAC adheres to independent innovation, with more than 170 invention patents. Different from the traditional chemical synthesis and fermentation industry, BONTAC has advantages of green low-carbon and high-value-added biosynthesis technology. What’s more, BONTAC has established the first coenzyme engineering technology research center at the provincial level in China which also is the sole in Guangdong Province.
In the future, BONTAC will focus on its advantages of green, low-carbon and high-value-added biosynthesis technology, and build ecological relationship with academia as well as upstream/downstream partners, continuously leading the synthetic biological industry and creating a better life for human beings.
Unlocking the Secrets of NMN: Mechanism and Effects on Health
In the world of cutting-edge biotechnology, few compounds have garnered as much attention as Nicotinamide Mononucleotide, or NMN. This revolutionary molecule is taking the health and wellness industry by storm, and for a good reason. In this article, we will explore what NMN is, its mechanisms, and its profound effects on health.
What is NMN?
Nicotinamide Mononucleotide (NMN) is a naturally occurring compound found in all living cells. It plays a crucial role in the production of Nicotinamide Adenine Dinucleotide (NAD+), a coenzyme that is essential for various biological processes in the body. NAD+ levels tend to decline as we age, contributing to various age-related health issues. NMN supplementation aims to boost NAD+ levels, potentially reversing or mitigating these issues.
The Mechanism: How NMN Works
NMN is a precursor to NAD+, meaning it is converted into NAD+ in our cells. This transformation is vital because NAD+ is involved in several critical cellular functions, including energy metabolism, DNA repair, and gene expression. When NMN is administered, it enhances the NAD+ levels, providing the body with more of this essential coenzyme.
Effects of NMN on Health
The increased availability of NAD+ through NMN supplementation has far-reaching effects on health and wellness:
1、Energy Production: NAD+ is a key player in the production of adenosine triphosphate (ATP), the body's primary energy currency. More NAD+ means more energy for the body's cells, potentially leading to increased vitality and stamina.
2、Cellular Repair: NAD+ supports DNA repair mechanisms, helping to maintain the integrity of the genome. This is crucial in preventing mutations that can lead to aging and the development of diseases.
3、Sirtuin Activation: NAD+ is necessary for the activation of sirtuins, a family of proteins that regulate cellular health. Sirtuins have been associated with longevity and can help combat age-related issues.
4、Metabolic Health: Increased NAD+ levels can have a positive impact on metabolic processes, potentially aiding in weight management and preventing metabolic disorders.
5、Neuroprotection: Some studies suggest that NAD+ augmentation with NMN may help protect against neurodegenerative diseases like Alzheimer's and Parkinson's.
6、Cardiovascular Health: NAD+ plays a role in maintaining healthy blood vessels, which can contribute to cardiovascular health.
7、Immune System Support: NAD+ helps regulate the immune system, potentially enhancing its ability to respond to infections and diseases.
Is NMN Safe?
NMN is generally considered safe for use, and it has been extensively studied in animal models. However, more research is needed to fully understand its long-term effects in humans. As with any supplement, it's crucial to consult with a healthcare professional before incorporating NMN into your health regimen.
In conclusion, NMN is a remarkable compound with the potential to revolutionize health and wellness. By increasing NAD+ levels, NMN supplementation can positively impact energy levels, cellular repair, metabolic health, and more. As the biotechnology industry continues to explore the possibilities of NMN, it may become a key player in the quest for longevity and enhanced well-being.
At Bontac, we are at the forefront of providing high-quality NMN raw materials for businesses in the health and wellness industry. Our commitment to quality and innovation ensures that our partners can harness the full potential of NMN. Contact us to learn more about our NMN offerings and how we can assist your business in delivering cutting-edge products to the market.
NMN: Manufacturing, Preparation, and Clinical Trials
In the realm of cutting-edge biotechnology, one compound has taken center stage for its potential to transform the landscape of health and wellness. Nicotinamide Mononucleotide (NMN) has been the subject of significant research, with a focus on its manufacturing and preparation processes, as well as its clinical trials.
NMN Manufacturing and Preparation
NMN is a derivative of niacin (vitamin B3) and is a precursor to Nicotinamide Adenine Dinucleotide (NAD+), a critical coenzyme involved in various cellular functions. Producing NMN involves several steps to ensure its purity and effectiveness:
1、Extraction: NMN can be synthesized from niacin or obtained through the extraction of natural sources like milk. These sources contain precursors that can be converted into NMN.
2、Purification: After extraction, NMN must undergo purification processes to remove impurities and achieve the desired level of purity. High purity is essential to ensure the efficacy and safety of NMN supplements.
3、Synthesis: Chemical synthesis is another method for manufacturing NMN. This involves converting niacin into NMN through a series of chemical reactions. This method offers precise control over the NMN production process.
4、Quality Control: Throughout the manufacturing process, rigorous quality control measures are applied to guarantee the safety and effectiveness of the final product. These measures include testing for purity, potency, and absence of contaminants.
The manufacturing and preparation of NMN require careful attention to detail to ensure that the end product meets the highest standards for quality and safety.
NMN Clinical Trials
Clinical trials related to NMN have provided valuable insights into its potential benefits. These trials have explored various aspects of NMN supplementation, shedding light on its safety and effectiveness:
1、Aging and Longevity: Some studies have suggested that NMN supplementation may have a positive impact on aging-related issues, potentially extending lifespan and improving overall health.
2、Metabolic Health: Clinical trials have examined the effects of NMN on metabolic health. Preliminary results have indicated potential benefits in areas such as glucose metabolism and insulin sensitivity.
3、Cardiovascular Health: Research has investigated the impact of NMN on cardiovascular health. Promising findings have emerged regarding blood vessel function and blood pressure regulation.
4、Neuroprotection: NMN's potential neuroprotective properties have been studied in the context of neurodegenerative diseases. While more research is needed, early results have been encouraging.
5、Safety and Tolerability: Clinical trials have also focused on the safety and tolerability of NMN. Generally, NMN has been well-tolerated, with few reported side effects.
It's important to note that while these clinical trials have provided valuable data, the research on NMN is ongoing, and more extensive studies are needed to establish its long-term safety and efficacy.
Bontac, a leading biotech enterprise, is at the forefront of providing high-quality NMN raw materials. Our commitment to innovation and quality ensures that our partners can develop products that meet the highest standards in the health and wellness industry. With a strong emphasis on research and development, we aim to contribute to the ongoing exploration of NMN's potential benefits.
In conclusion, NMN manufacturing and preparation involve a series of rigorous steps to ensure the production of high-quality, safe supplements. Clinical trials have provided promising insights into NMN's potential benefits in areas such as aging, metabolic health, cardiovascular health, and neuroprotection. As research on NMN continues, Bontac remains dedicated to providing the industry with the finest NMN raw materials for the development of innovative health and wellness products.
Best NMN Powder: Factory, Purity, and Supplier
When searching for the best NMN (Nicotinamide Mononucleotide) powder, three key aspects play a pivotal role in your decision-making process. This comprehensive guide dives into the world of NMN, highlighting the critical factors that set the best NMN powder apart. We'll explore the best NMN powder factory, delve into the significance of purity, and introduce you to a reliable NMN powder supplier.
- Best NMN Powder Factory :
- State-of-the-Art Manufacturing:
The foundation of premium NMN powder begins at the factory. Look for a manufacturer that boasts state-of-the-art facilities, adhering to the highest standards of production. Top-tier factories utilize cutting-edge technology and rigorous quality control to ensure the finest NMN powder.
- Research and Development:
Leading NMN powder factories invest in robust research and development. They actively engage in scientific studies and collaborate with experts to continuously enhance their product's quality and effectiveness.
- Quality Certifications:
Reputable factories hold certifications such as GMP (Good Manufacturing Practices) and ISO, underscoring their commitment to quality, safety, and consistency. These certifications are a testament to their dedication to producing the best NMN powder.
- Best NMN Powder Purity (approx. 200 words):
- High Purity Standards:
The purity of NMN powder is paramount. Opt for a product with a purity rating of 99% or higher. The best NMN powder is free from impurities and excipients, ensuring maximum potency.
- Independent Testing:
To validate purity claims, the best NMN powder undergoes independent third-party testing. These tests provide transparency and assurance that what you're purchasing aligns with its purity claims.
- No Additives or Fillers:
A top-quality NMN powder doesn't contain additives or fillers. The absence of unnecessary substances ensures you're receiving a pure and potent product.
- Best NMN Powder Supplier:
- Reliability and Reputation:
Selecting the right supplier is crucial. Look for a supplier with a stellar reputation for delivering consistent, high-quality NMN powder. Online reviews and testimonials can offer insights into their reliability.
- Transparent Sourcing:
A trustworthy supplier should be transparent about the sourcing and production of their NMN powder. Clear information about their supply chain and production process demonstrates their commitment to quality.
- Customer Support:
The best NMN powder supplier offers excellent customer support. Whether you have questions or need assistance, a responsive and knowledgeable support team is a valuable asset.
In the quest for the best NMN powder, the factory, purity, and supplier are non-negotiable elements. By opting for a manufacturer with cutting-edge facilities, a commitment to purity, and a reliable supplier with a sterling reputation, you'll embark on a journey towards reaping the full benefits of NMN. The best NMN powder is not just a product; it's a commitment to your well-being.
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Raising Chilled Ram Sperm Quality with NMN
Introduction Artificial insemination with chilled ram semen is commonly used method in livestock industry. But storing sperm in chilled conditions may cause changes in sperm membrane function and structure, and shortens its lifespan. Notably, supplementation of β-nicotinamide mononucleotide (NMN) can raise ram sperm quality during storage at 4°C. Merits of artificial insemination with chilled ram semen The adoption of artificial insemination with chilled ram semen can ensure good breeding stock and accelerate the reproduction. By this way, the risk of diseases such as vibriosis, trichomoniasis, vaginitis, leptospirosis and brucellosis, which are transmitted by rams in natural breeding, can be reduced to a large extent. In addition, this method allows crossbreeding or purebreeding, and reduces the number of rams to be bred, which is beneficial and cost-effective. Importantly, this method can greatly avoid the risk of dystocia or injury due to the big size difference between rams and ewes during breeding. Chilled semen can be preserved semi-permanently to send far away, avoiding the trouble of transporting or moving breeding animals. The beneficial role of NMN in improving ram sperm quality Supplementation of NMN markedly improves the sperm motility, as evidenced by the obvious increases in the motility parameters such as total motility, progressive motility, straight-line velocity (VSL), average path velocity (VAP), linearity (LIN), curvilinear velocity (VCL), and straightness (STR). Meanwhile, NMN maintains the plasma membrane integrity and acrosome integrity. Note: (Figure A) White arrow: viable sperm with intact acrosome; green arrow: viable sperm with damaged acrosome; orange arrow: dead sperm with damaged acrosome; black arrow: dead sperm with intact acrosome (Figure B) White arrow: sperm with an intact plasma membrane; orange arrow: sperm with a damaged plasma membrane What’s more, NMN elevates the mitochondrial activity and antioxidant capacity, while reducing the sperm oxidative stress and apoptosis, as manifested by the downregulation of Cleaved-Caspase 3, Cleaved-Caspase 9, Bax, LPO, MDA, and ROS, as well as upregulation of Bcl-2, GSH and SOD in sperm. NMN as an anti-oxidant to improve ram sperm quality NMN can reduce ROS level and ROS-induced sperm damage to improve the quality of sperm, which may be attributed to its anti-oxidant property. Ram sperm contains a high content of PUFA in its plasma membrane, it is susceptible to oxidative stress. The antioxidants (enzymatic and non-enzymatic) in sperm can reduce free radicals to maintain sperm redox homeostasis and quench excessive ROS to prevent damage to sperm cells. Conclusion Supplementation of NMN can improve chilled ram sperm quality in vitro by reducing oxidative stress damage, showing its great potential in reproduction and breeding activities. The premium dosage of NMN vary in species. In view of its significant effect on ram sperm quality, the preferred dosage of NMN in this research is 60 μM. Reference Zhu Z, Zhao H, Yang Q, et al. β-Nicotinamide mononucleotide improves chilled ram sperm quality in vitro by reducing oxidative stress damage. Anim Biosci. 2024;37(5):852-861. DOI: https://doi.org/10.5713/ab.23.0379 BONTAC NMN BONTAC is the pioneer of NMN industry and the first manufacturer to launch NMN mass production, with the first whole-enzyme catalysis technology around the world. At present, BONTAC has become the leading enterprise in niche areas of coenzyme products. Our services and products have been highly recognized by global partners. Furthermore, BONTAC has the first national and the only provincial independent coenzyme engineering technology research center in Guangdong, China. The coenzyme products of BOMNTAC are widely used in fields such as nutritional health, biomedicine, medical beauty, daily chemicals and green agriculture. Disclaimer This article is based on the reference in the academic journal. The relevant information is provided for sharing and learning purposes only, and does not represent any medical advice purposes. If there is any infringement, please contact the author for deletion. The views expressed in this article do not represent the position of BONTAC. Under no circumstances will BONTAC be responsible or liable in any way for any claims, damages, losses, expenses, or costs arising directly or indirectly from your reliance on the information and material on this website.
Elevating Wellness: BONTAC's NMN Powder Offerings
Elevating Wellness: BONTAC's NMN Powder Offerings As we delve into the realm of health and wellness, the spotlight shines brightly on NMN powder, a powerful supplement embraced by many for its potential benefits. At BONTAC, we take pride in offering a premium selection of NMN powder formulations designed to support optimal health and vitality. Our commitment to excellence shines through in our dedication to scientific innovation, top-notch technical support, and unwavering focus on quality. Join us on a journey to explore the transformative effects of BONTAC's NMN powder offerings. Exploring BONTAC's NMN Powder Selection BONTAC's NMN powder selection stands out as a cornerstone of our commitment to promoting wellness. We meticulously source and formulate our NMN powder to ensure the highest purity and efficacy, setting a gold standard in the industry. With a focus on quality and potency, BONTAC's NMN powder are designed to support cellular health, energy production, and overall well-being. Whether you require cutting-edge laboratory equipment, innovative research tools, or transformative bio-based materials, BONTAC has you covered. Our extensive product portfolio spans a wide spectrum, including but not limited to genetic engineering tools, biomaterials, diagnostic assays, regenerative medicine solutions, and environmental sustainability innovations. By providing access to these advanced biotechnology products, we empower businesses to stay ahead of the curve and drive progress in their respective fields. Features and Purity of BONTAC's NMN Powder The hallmark of BONTAC's NMN powder offerings lies in their exceptional quality and purity standards. Our products undergo rigorous testing and quality control measures to guarantee maximum effectiveness and safety. Customers trust in the purity and authenticity of BONTAC's NMN powder, knowing that they are investing in products that deliver tangible results and contribute to their wellness journey. Leveraging BONTAC's NMN Powder for Optimal Health Integrating BONTAC's NMN powder into your daily wellness regimen opens doors to a world of health benefits. Our team is dedicated to providing unparalleled technical support and expertise to guide you through the supplementation process. Partnering with BONTAC ensures that you have access to premium NMN formulations backed by scientific research and innovation, empowering you to achieve your health goals with confidence. Conclusion In conclusion, BONTAC's NMN powder offerings represent a commitment to holistic wellness and vitality. With a focus on excellent products, technical innovation, and unwavering customer support, we stand as your trusted partner in the journey toward optimal health. Embrace the power of BONTAC's premium NMN powder and elevate your well-being to new heights.
Powering Health and Vitality: BONTAC's Metabolism-boosting Product Portfolio
Powering Health and Vitality: BONTAC's Metabolism-boosting Product Portfolio In the dynamic landscape of health and wellness, the demand for cutting-edge metabolism-boosting products continues to soar. At BONTAC, we are proud to offer a diverse range of metabolism-boosting products meticulously designed to enhance cellular function, optimize metabolism-boosting health, and support overall well-being. The world of metabolism-boosting products has witnessed a remarkable evolution, and as trailblazers in the industry, BONTAC understands the significance of staying at the forefront of metabolism-boosting product development. Our dedicated team of experts tirelessly engages in research and innovation, ensuring that our metabolism-boosting products remain on the cutting edge of the industry. By constantly pushing boundaries and challenging conventional norms, we strive to deliver products that exceed expectations and address the ever-evolving needs of our valued customers. The Evolution of metabolism-boosting Products As pioneers in the industry, BONTAC recognizes the importance of staying ahead of the curve in metabolism-boosting product development. Our team of experts works tirelessly to research and innovate, ensuring that our metabolism-boosting products are at the forefront of the industry. Through a commitment to excellence and continuous improvement, we strive to meet the evolving needs of our customers. Through a steadfast commitment to excellence and a relentless pursuit of continuous improvement, we are able to anticipate emerging trends and embrace groundbreaking advancements in metabolism-boosting science. This enables us to develop innovative formulations that meet or even surpass the expectations of our discerning clientele. By harnessing the power of scientific knowledge and leveraging the latest technologies, we create metabolism-boosting products that are not only effective but also safe, reliable, and tailored to the unique requirements of individuals seeking to optimize their metabolism-boosting health. Benefits of BONTAC's metabolism-boosting Product Range BONTAC's metabolism-boosting product range is crafted with precision to enhance cellular function and energy metabolism. Our products are formulated to support optimal metabolism-boosting health, providing a foundation for long-term wellness. From boosting energy levels to optimizing metabolism-boosting processes, BONTAC's metabolism-boosting products are designed to empower individuals to live their best and healthiest life. Collaborating with BONTAC for metabolism-boosting Success When you partner with BONTAC, you gain access to customized solutions tailored to your unique business needs. Our team is dedicated to providing top-tier technical support and expertise in the metabolism-boosting industry, ensuring that you receive the guidance and resources necessary to achieve success. By partnering with BONTAC, you can leverage our commitment to technical innovation and tap into our extensive business coverage to reach new heights in the health and wellness market. Conclusion In conclusion, BONTAC's metabolism-boosting product portfolio represents the pinnacle of excellence, technical innovation, and unwavering commitment to customer success. Our products are characterized by their effectiveness, quality, and unique features that set them apart in the market. Join us on the journey to better health and vitality with BONTAC's exceptional metabolism-boosting products that are designed to transform life and empower individuals to thrive.