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Dissection on the promising potential of NMN in treating atherosclerosis
Dissection on the promising potential of NMN in treating atherosclerosis

1. Introduction Atherosclerosis is a chronic progressive inflammatory disease, which is featured by the accumulation of lipids in the intima of the arteries with yellow appearance. This disease

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How to Maintain NAD+ Homeostasis to Regulate Mitochondrial and Cardiac Function
How to Maintain NAD+ Homeostasis to Regulate Mitochondrial and Cardiac Function

1. Introduction Mitochondria are the center of energy metabolism in cardiomyocytes, which are necessary for maintaining normal myocardial contractility and cardiac function. Typically, the de

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Delving into the Function of Ginsenoside Rh2 in the Develpoment of Breast Cancer
Delving into the Function of Ginsenoside Rh2 in the Develpoment of Breast Cancer

1. Introduction According to the 2020 report of World Health Organization (WHO), there are approximately 2.3 million cases with breast cancer worldwide. Breast cancer has emerged as one of the

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The Significance of NAD+ in Intestinal Senescence Caused by Elevated mtDNA Mutations
The Significance of NAD+ in Intestinal Senescence Caused by Elevated mtDNA Mutations

1.Introduction The senescence in mammals is generally concomitant with the dysregulation of intestinal homeostasis and the accumulation of mitochondrial DNA (mtDNA) mutations. High-burden mtDNA mutations lead to N

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The Immuno-Enhancing Effect of Rh2-L on Double Emulsion Adjuvant Against Foot-and-Mouth Disease
The Immuno-Enhancing Effect of Rh2-L on Double Emulsion Adjuvant Against Foot-and-Mouth Disease

1. Introduction At present, vaccine is the preferred option for the prevention of foot-and-mouth disease (FMD), for which the adjuvant is essential due to its strong role in boosting immune response associated wi

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Good News! BONTAC has been selected as “2023 Deloitte China Life Sciences & Healthcare Rising Star”
Good News! BONTAC has been selected as “2023 Deloitte China Life Sciences & Healthcare Rising Star”

1. Introduction On January 9, 2024, the expert team of selection organizing committee from Deloitte visited BONTAC, and presented the trophy of “China Life Sciences & Healthcare Rising Star” t

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NMN Administration: a Novel Therapeutic Direction for Sepsis-induced Acute Lung Injury
NMN Administration: a Novel Therapeutic Direction for Sepsis-induced Acute Lung Injury

1. Introduction Acute lung injury comprises a uniform response of the lung to inflammatory or chemical insults which is commonly caused by systemic illness including sepsis or trauma, infection with pathogens, and tox

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Probing the Magic Role of NAD+ Metabolism-associated Genes in Gastric Cancer
Probing the Magic Role of NAD+ Metabolism-associated Genes in Gastric Cancer

  1. Introduction Gastric cancer (GC) represents a global health-care challenge, which is the fifth most common cancer and the fourth leading cause of cancer death across the world in 2020, with a significant

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A Scientific Method for Quantifying NMN in Biological Samples
A Scientific Method for Quantifying NMN in Biological Samples

1. Introduction Supplementation of nicotinamide mononucleotide (NMN) to upregulate the level of nicotinamide adenine dinucleotide (NAD+) has been unveiled to be a promising anti-aging intervention. However, it is

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