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Introduction In response to the escalating global obesity rates, the demand for sugar reduction has reached a critical juncture. As a strategic pivot, the food industry has increasingly incorporated sugar substitutes,

Introduction Parkinson's disease (PD), known as the silent killer, has emerged as the second most common chronic neurodegenerative disease in the world after Alzheimer's disease, affecting 

  Introduction Nicotinamide adenine dinucleotide (NAD+) is a critical coenzyme in cells, a central cofactor of redox reaction and a central regulator of various metabolisms in the human body. It is involved in a

  Introduction Spinal cord injury (SCI) can lead to severe impairments in motor, sensory, and autonomic nervous system functions. It has been reported that motor function recovery can be promoted by mediatin

  Introduction Chronic cerebral hypoperfusion (CCH) has been identified as one of the initial conditions critical to the development of cognitive impairment, which is tightly associated to the complex neurologic

  Introduction Stroke remains the second leading cause of death and the third leading cause of death and disability combined in the world, as reported in 2019 Global Burden of Disease Study. Ischemic stroke

  Introduction Myocardial ischemia/reperfusion (MI/R) can damage the heart muscle, which may contribute to further cardiomyocyte death. Following percutaneous coronary intervention therapy, patients with MI/

  Introduction According to the report by World Health Organization (WHO) in 2017, depression is the third leading cause of the global disease burden, with over 300 million people suffering from this disease w

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