Ginseng, a storied herb in traditional medicine, has been used for millennia for its myriad health benefits. Central to its medicinal prowess are ginsenosides, potent saponins that have piqued the interest of the mod
Ginseng, revered for centuries in traditional Chinese medicine, is a root known for its remarkable therapeutic properties. Central to its efficacy are ginsenosides, a diverse group of saponins considered the active s
Nicotinamide Adenine Dinucleotide Phosphate (NADP), a crucial coenzyme in cellular metabolism, serves as a cornerstone in numerous biochemical reactions. As a derivative of NAD, it adds a phosphate group which enhan
The world of biochemistry is replete with molecules that, while not always in the limelight, play critical roles in the maintenance and regulation of cellular processes. Among these, oxidized coenzymes stand out for thei
In the intricate world of biochemistry, coenzymes play pivotal roles in facilitating numerous metabolic reactions essential for life. One such crucial coenzyme is Nicotinamide Adenine Dinucleotide Phosphate (NADP). This
In the world of natural sweeteners, stevia has carved out a significant niche thanks to its exceptional sweetness and health benefits. Derived from the leaves of the Stevia rebaudiana plant, this zero-calorie sweetener h
In the world of dietary substances, every detail matters—from the source of the ingredients to the color of the final product. For those curious about the health benefits of Nicotinamide Mononucleotide Hydrogen (NM
In the evolving landscape of health and wellness substances, the quest for more effective solutions to combat aging and boost cellular health is perpetual. Among the forefront of these advancements is the use of NAD+ enh
In the expansive world of biochemical research and health preservation, certain compounds emerge as particularly significant due to their potential applications and benefits. One such compound is NMNH, which sta
Nicotinamide adenine dinucleotide hydrogen (NADH) is a lesser-known yet crucial molecule in the biological sciences and various health-related fields. In this blog, we explore the wide-ranging applications of NA
In the pursuit of maintaining youthful energy and health as we age, scientific research continues to bring forward new substances that can aid in this quest. One of the most promising of these is Beta-Nicotinamide Mononu
In the quest for optimal health and vitality, understanding the role of coenzymes in cellular function is paramount. Nicotinamide Adenine Dinucleotide Hydrogen (NADH) is one such coenzyme that plays a critical r
Nicotinamide adenine dinucleotide (NAD+) is a cornerstone of cellular health, playing a pivotal role in the energy production and metabolic processes that sustain life. As we age, levels of NAD+ naturally decline, leadin
Energy metabolism is a crucial biological process that involves converting food into the energy needed to power all cellular activities. It is fundamental to maintaining health, vitality, and overall well-being. One
In the realm of health and wellness, maintaining optimal cellular function is key to overall vitality and longevity. One molecule that is central to numerous biological processes is Nicotinamide Adenine Dinucleotide, com
In the quest for vitality and longevity, the scientific breakthroughs surrounding Nicotinamide Mononucleotide (NMN) have captured the attention of health enthusiasts worldwide. BONTAC, a leader in biochemical innovat
In the quest for health and longevity, scientific breakthroughs often lead us to natural compounds that can significantly improve our well-being. One such compound that has captured the attention of the health and wellne
In the fast-evolving sector of biotechnology, products derived from biological processes and organisms are reshaping industries from healthcare to agriculture. The biotechnology product market is fiercely competitive, wi
In the dynamic world of health and biotechnology, cellular rejuvenation stands out as a revolutionary concept, promising a new era of enhanced health, prolonged youth, and improved quality of life. As a leader in the glo
In the rapidly evolving landscape of health and wellness, metabolism-boosting products have emerged as key components in enhancing human health, optimizing metabolic processes, and supporting various bodily functi
Introduction In the realm of animal husbandry, feed additives are necessary as they can not only improve the nutritional value of feed and optimize the internal environment of the rumen, but also enhance
Introduction Nicotinamide adenine dinucleotide (NAD) deficiency has been linked to a range of renal disorders, encompassing conditions such as acute kidney injury, diabetic nephropathy, adenine-triggered kidney diseas
Introduction In response to the escalating global obesity rates, the demand for sugar reduction has reached a critical juncture. As a strategic pivot, the food industry has increasingly incorporated sugar substitutes,
Introduction Parkinson's disease (PD), known as the silent killer, has emerged as the second most common chronic neurodegenerative disease in the world after Alzheimer's disease, affecting
Introduction Nicotinamide adenine dinucleotide (NAD+) is a critical coenzyme in cells, a central cofactor of redox reaction and a central regulator of various metabolisms in the human body. It is involved in a
Introduction Spinal cord injury (SCI) can lead to severe impairments in motor, sensory, and autonomic nervous system functions. It has been reported that motor function recovery can be promoted by mediatin
Introduction Chronic cerebral hypoperfusion (CCH) has been identified as one of the initial conditions critical to the development of cognitive impairment, which is tightly associated to the complex neurologic
Introduction Stroke remains the second leading cause of death and the third leading cause of death and disability combined in the world, as reported in 2019 Global Burden of Disease Study. Ischemic stroke
Introduction Myocardial ischemia/reperfusion (MI/R) can damage the heart muscle, which may contribute to further cardiomyocyte death. Following percutaneous coronary intervention therapy, patients with MI/
Introduction According to the report by World Health Organization (WHO) in 2017, depression is the third leading cause of the global disease burden, with over 300 million people suffering from this disease w
Thanks to our unrelenting dedication to creating cutting-edge solutions that push the frontiers of scientific development, BONTAC has long been at the forefront of the biochemical sector. We are excited to present o
Our unshakable dedication to maximizing the potential of traditional Chinese medicine has propelled BONTAC to the forefront of the natural products sector for a considerable amount of time. We are thrilled to presen
Our unwavering quest of innovation at BONTAC has always been sparked by our profound grasp of the natural world and its unrealized potential. We are excited to present our ground-breaking solutions today, which are
With an unwavering zeal for creating innovative solutions with the potential to revolutionize industries and improve lives, we at BONTAC have long been at the forefront of the green biotechnology revolution. We are
With an unwavering zeal for creating innovative solutions with the potential to revolutionize industries and improve lives, BONTAC has long been at the forefront of the green biotechnology revolution. We are ex
For many years, BONTAC has been acknowledged as a leader in the field of green biotechnology, thanks to our unwavering commitment to creating ground-breaking products and services that have the potential to improve
Because of our unwavering search for products that have the power to genuinely change the lives of our partners and consumers, we at BONTAC have long been at the forefront of cutting-edge green biotechnology solutio
Being deeply aware of the vital role our products play in enabling people to live healthier, more fulfilling lives has always motivated us at BONTAC to innovate. We are pleased to announce our ground-breaking NMNH,
Propelled by an unwavering dedication to innovation and a profound comprehension of the crucial function this coenzyme plays in preserving cellular health and lifespan, BONTAC has been at the forefront of the NAD+ a
At BONTAC, we have always been driven by a relentless pursuit of innovation – a desire to push the boundaries of what is possible in the realm of nutritional supplements and biomedical research. Today, we are thril
At BONTAC, we have long been passionate about the pursuit of cutting-edge nutritional solutions that can truly transform human health and wellness. Today, we are excited to shine a spotlight on one of the most remarkable
At BONTAC, we have always been at the forefront of cutting-edge nutraceutical research, dedicated to uncovering the most remarkable and transformative compounds nature has to offer. Today, we are thrilled to introduce ou
For many years, BONTAC has been at the forefront of innovative biopharmaceutical developments, committed to maximizing the life-changing potential of nature's most extraordinary substances. We are excited to pre
At BONTAC, we have long been at the forefront of innovation in the realm of biopharmaceuticals, dedicated to harnessing the power of cutting-edge scientific discoveries to improve the lives of those we serve. Today, we a
At BONTAC, we are driven by a profound commitment to empowering individuals with the tools they need to achieve optimal health and well-being. As industry leaders in the realm of biotechnology, we have dedicated ourselve
At BONTAC, our mission is to empower individuals with the tools they need to achieve optimal health and wellness. As the pioneer in the realm of biotechnology, we have dedicated ourselves to uncovering the profound benef
At BONTAC, we are deeply committed to advancing the frontiers of human health and wellness. As a leading innovator in the field of biotechnology, we have been focused on harnessing the incredible potential of Beta-Nicoti
As a leading player in the world of biotechnology, BONTAC is at the forefront of driving innovation and transforming the industry. Our unwavering commitment to scientific excellence and our deep understanding of the
At BONTAC, we are driven by a relentless pursuit of innovation and a deep commitment to improving the lives of those we serve. As leaders in the realm of cellular health and rejuvenation, we are excited to introduce our
At BONTAC, we are at the forefront of the metabolism-boosting product industry, driven by our unwavering commitment to innovation and the pursuit of scientific excellence. Our focus on developing cutting-edge solutions h
Introduction With changes in lifestyles and dietary structure, hyperuricemia shows an increasing prevalence year by year, which may become the second largest metabolic disease after diabetes mellitus, a
Introduction Steviol glycosides are secondary metabolites obtained by extracting and isolating stevia from the herbaceous plant Stevia rebaudiana of the Asteraceae family, with a high degree of sweetness
NAD is an abbreviation for nicotinamide adenine dinucleotide, which is a naturally occurring coenzyme (a substance that works with enzymes) found in our bodies. It helps cells produce energy. However, as we age, NAD
Introduction According to the report of International Agency for Research on Cancer (IARC), there are 19.3 million new cases of malignant tumors and 10 million deaths worldwide in 2020. Malignant tumors have overtaken
Introduction Elderly individuals are at a significantly higher risk for peripheral artery disease (PAD), a common vascular disorder. As the global population ages rapidly, the number of PAD cases is projected to rise
Introduction Diabetic kidney disease (DKD) has emerged as one of the primary cause of mortality among the patients with end-stage renal disease such as renal failure, accounting for 30-50% of chronic renal failure cas
Introduction Nicotinamide adenine dinucleotide (NAD+) metabolism is essential for maintaining normal physiological activities, and the decreased NAD+ level is related to various pathologies such as cardiac dis
Introduction Targeting the autophagy-NAD axis has been reported be a viable therapeutic strategy for Niemann-Pick type C1 (NPC1) disease. The study suggests that both pharmacological rescue of autophagy deficiency and
Introduction Apical periodontitis, an inflammatory disease affecting tooth apex tissues, is triggered by oral pathogens infecting the root canal. One of the main reason for endodontic treatment failure is Enterococcus
Introduction Amoebiasis has emerged as the third most common cause of death by parasites worldwide after malaria and schistosomiasis infections. According to the report of World Health Organization, over 40 milli
Introduction Disturbance in hepatic NAD+ metabolism has been manifested as a key factor in the initiation and progression of nonalcoholic fatty liver disease (NAFLD), one of the most co
Introduction According to the 2017 Commission on Traumatic Brain Injury (TBI), TBI remains one of the top three causes of injury-related death and disability up to 2030. There are 50~60
Introduction In clinical settings, doxorubicin (DOX) is an effective broad-spectrum anti-cancer drug in chemotherapy for various tumors, including hematological malignancies and solid tumors such as leu
Introduction Cigarettes containing nicotine (Nic) and sugar-sweetened beverages (SSBs) with high fructose corn syrup (HFCS) have been uncovered to induce hepatic steatosis, which are the risk factors for the developme
Introduction Acute promyelocytic leukemia (APL), the M3 type of acute myeloid leukemia (AML), typically relies on all-trans retinoic acid (ATRA) as its primary treatment. While APL patients treated with
Introduction Recent research unveils that hepatic insulin resistance (IR) and steatosis in obesity have a strong association with endoplasmic reticulum (ER)-mitochondria miscommunication. Notably,
Aging is an undeniable reality of life. It is a known fact that with increasing age, different body functions tend to decline. While we may not completely stop this decline, we can slow it down with pure NMN po
Introduction In the presence of oxygen, tumors produce adenosine triphosphate (ATP) through glycolysis instead of mitochondrial oxidative phosphorylation, a phenomenon known as the “Warburg effect”. Aerobi
Introduction Age-related macular degeneration (AMD) has become one of the leading cause of low vision and even blindness in the elderly, especially in those above 50. In 2020, approximately 1.8 million people aged ove
Introduction Natural products, including single components or extracts of herbal medicines, have the features of good efficacy and low toxicity when used in tumor treatment. They have unique advantages in treating dis
Introduction Reproductive dysfunction is frequent in female suffering from type 1 diabetes (T1D), up to 40% of whom will develop a variety of reproductive dysfunctions throughout their lives. T1D patients often ha
In today's health industry, NADH (nicotinamide adenine dinucleotide), as an important coenzyme, is widely used to supplement energy and enhance immunity. It is crucial to choose high-quality, high-purity NADH powder.
In today's health and anti-aging fields, NMN (nicotinamide mononucleotide) has attracted a lot of attention. As an important cellular coenzyme, NMN plays a key role in maintaining cell health and delaying the aging p
Introduction Ginsenoside Rg3 (Rg3) holds great promise as a potential drug for preventing scar formation, but it is often difficult for it to work alone due to its poor water solubility and low bioavail
Introduction Lead (Pb) contamination in aquatic environments poses a significant threat to the health and well-being of aquatic organisms, including fish species. There is rising popularity of prebiotics and probi
Elevating Wellness: BONTAC's NMN Powder Offerings As we delve into the realm of health and wellness, the spotlight shines brightly on NMN powder, a powerful supplement embraced by many for its potential benefits.
Innovating Solutions: BONTAC's Biotechnology Product Offerings In the ever-evolving landscape of biotechnology products, BONTAC remains a trailblazer in providing cutting-edge solutions that drive innovation
Revolutionizing Biotechnical Research: BONTAC's Trailblazing Discoveries In the dynamic realm of biotechnical research, BONTAC stands at the forefront of innovation, dedicated to driving progress and breakthr
Elevating Health with BONTAC's Cutting-Edge Longevity Supplements In the realm of health and wellness, the demand for high-quality metabolism-boosting supplements continues to rise. At BONTAC, we recognize the c
Introduction It has been reported that infection with Gram-negative bacteria can disrupt the osteogenic differentiation. Notably, nicotinamide mononucleotide (NMN) protects against osteogenesis from inflammat
Pioneering Discoveries: BONTAC's Innovations in Biotechnical Research In the dynamic realm of biotechnical research, BONTAC stands at the forefront of innovation, dedicated to driving progress and breakthroug
Nourishing Wellness: BONTAC as a Leading Raw Material Supplier of Supplements As a prominent raw material supplier of supplements, BONTAC is dedicated to developing and delivering premium products that promote he
Unleash Vitality and Renewal: BONTAC's Cutting-edge Cellular Rejuvenation Solutions Cellular Rejuvenation plays a vital role in enhancing vitality and promoting overall wellness. At BONTAC, we are dedicated t
Introduction Hepatocellular carcinoma (HCC) is hypervascular solid tumor with rapid deterioration, poor overall prognosis and a high recurrence rate, accounting for 90% of primary liver cancers, which ha
Elevating Wellness: BONTAC Advanced Raw Materials for Cellular Health Supplements In today's fast-paced world, the quest for optimal health and wellness has led to a surge in the demand for high-quality cellular
Powering Health and Vitality: BONTAC's Metabolism-boosting Product Portfolio In the dynamic landscape of health and wellness, the demand for cutting-edge metabolism-boosting products continues to
Unlocking the Power of Metabolism-Boosting Supplements: A Guide by BONTAC In the realm of health and wellness, the demand for high-quality metabolism-boosting supplements is steadily rising. At BONTAC,
Introduction Artificial insemination with chilled ram semen is commonly used method in livestock industry. But storing sperm in chilled conditions may cause changes in sperm membrane function and structure, and
Introduction In light of a statistics report by World Health Organization (WHO), there are 18 million people suffering from rheumatoid arthritis (RA) worldwide in 2019, where the prevalence of female is 2.5 times
Introduction Glaucoma is regarded as the second dominant cause of blindness across the world. With the amounting number and proportion of elderly people, it is estimated that 111.8 million people will have glaucom
Introduction Triocresyl phosphate (TOCP) is widely used in the realm of industry and agriculture in the last century. However, it is subsequently banned due to the increasing understanding of its toxicity. In
Introduction Cardiovascular diseases (CVD) poses huge economic burden and great threat to the life of patients, even surpassing Alzheimer's disease and diabetes. 17.9 million people in the world
Introduction Myocardial ischemia-reperfusion (I/R) injury has emerged as an urgent clinical issue that may offset the benefits of reperfusion therapy and even worsen the prognosis of acute myocardial infarction, a
.two-side{ text-align: justify; display: flex; justify-content: space-between; } Introduction The crucial parts of nicotinamide adenine dinucleotide (NAD+) and its metabolites in aging a
Introduction Ginsenoside Rh2 nanoliposome formulation has been proved to effectively target and deliver drugs to the tumor site, with less side effects and higher treatment efficiency, holding great promise in the
Introduction Replenishing nicotinamide mononucleotide (NMN) to raise the availability of nicotinamide adenine dinucleotide (NAD+) has been deemed as effective approach to prevent neurodegeneration in aging and pat
Introduction Rare ginsenoside Rg3, an active extract from Panax ginseng, is reported to possess a wide range of pharmacological properties including anti-angiogenesis and anti-cancer, with high lipophilicity (esti
Introduction Wound healing is a sophisticated process responding to tissue damage, which is associated with numbers of interaction of various cell types, cytokines, growth factors, and other molecules. Strikingly,
Introduction Diabetes is one of the dominant causes of death and disability worldwide, greatly affecting the life quality of patients. According to the latest data on diabetes released by the Lancet (GBD Study 202
Introduction Intervertebral disc degeneration (IDD) is a frequently seen orthopedic disease, which is accompanied with excessive apoptosis of nucleus pulposus cells (NPCs) and degeneration of extracellular ma
Introduction Ginsenoside Rg3 is Panaxanediol type tetracyclic triterpenoid saponin monomer extracted from the root of Panax ginseng, which has a wide range of pharmacological effects including anti-tumor, neuroprotect
Introduction The gut is a diverse and dynamic microbiotic system. There are about 100 trillion microorganisms in the gut, which is mainly composed of anaerobic, partially anaerobic, and aerobic bacteria. In the pr
Introduction Mar 4th is determined as the World Obesity Day. World Obesity Federation, UNICEF and WHO have hosted a global youth-led webinar to talk about obesity & youth. The obesity crisis has gradually attr
Introduction Nicotinamide mononucleotide (NMN), one precursor of nicotinamide adenine dinucleotide (NAD+), has been ascertained to be implicated with multiple biological processes such as cellular redox regulation and
Introduction Alpers' disease is both a neurodegenerative disorder and a metabolic disorder, which is tightly linked to mitochondrial dysfunction and mutations in the catalytic subunit of polymerase
Introduction NADH (reduced form of NAD+) serves as a carrier of biological hydrogen and an electron donor, which participates in diverse physiological processes such as protein synthesis, DNA repair,
Introduction Ginsenoside Rh2, one protopanaxadiol (PPD)-type rare ginsenoside in Panax ginseng, is uncovered to possibly have broad-spectrum pharmacological activity in diversified tumors. It is utili
Introduction Solute carrier family 25 member 51 (SLC25A51) is perceived as a mammalian transporter, which is capable of importing oxidized nicotinamide adenine dinucleotide (NAD+) into mitochondrial matrix. Remark
Introduction Oxidized form of nicotinamide adenine dinucleotide (NAD+) and its precursor nicotinamide mononucleotide (NMN) have been uncovered to restore DNA repair and prevent cancer progression via the deleted i
1. Introduction Disrupted nicotinamide adenine dinucleotide (NAD+) metabolism is increasingly deemed to be one of risk factor for amendable cardiovascular disorders. A substantial evidence has mirrored that res
1. Introduction Rare ginsenosides, a group of dammarane triterpenoids that exist in low natural abundance, fuels a high concern from scholars recently, showing great potential as shining components in drugs and nu
1. Introduction Nicotinamide adenine dinucleotide (NAD) has been unveiled to be essential for embryonic development. Patients with genetic variants in the NAD+ de novo synthesis pathway often have congen
1. Introduction The gut microbiota has long been regarded as one of the key elements contributing to the regulation of host health. Any changes in the composition or quality of the gut microbiota may have physiolo
1. Introduction Nicotinamide adenine dinucleotide (NAD) compartmentalized in adipocytes can modulate adipocyte differentiation and gene expression, in addition to controlling glucose metabolism. White adipose tiss
1. Introduction Nicotinamide mononucleotide (NMN) supplementation has been suggested to hamper the inflammatory responses via restoring NAD+ level and downregulating the expression of C
1. Introduction Age-related NAD+ depletion affects physiological functions and contributes to various aging-related diseases. NAD+ precursors can significantly elevate NAD+ level in murine tissues, effectivel
1. Introduction In mammalian cells, the majority of NAD+ is produced from metabolites entering the NAD+ salvage pathway. Nicotinamide phosphoribosyltransferase (NAMPT) is the rate-limiting enzyme of the salvage
Nmnh, also known as nicotinamide mononucleotide hydrate, is a vital coenzyme found in all living cells. It plays a crucial role in cellular metabolism, energy production, and various biosynthetic processes. High purity N
In the realm of health supplements, NADH stands out as a crucial coenzyme involved in cellular metabolism. Its importance in maintaining energy levels and supporting overall well-being has made it a prized ingredient for
1. Introduction Nicotinamide Mononucleotide (NMN) has been deemed as a functional nutrient for improving human intestinal health. In this study, an in vitro simulated digestion model
1. Introduction Amyotrophic lateral sclerosis (ALS) is a progressive fatal neurodegenerative disease that affects the motion-related nerve cells in the brain and spinal cord. The disease is featured by the d
1.Introduction A series of neurodegenerative diseases, such as Alzheimer's disease, Parkinson's disease and Huntington's disease, are accompanied with bioenergetic maladaptations and axonopathy wi
1. Introduction Diabetic peripheral neuropathy (DPN) is one of the most frequent complications of diabetes, ans also a major cause of foot ulcers, disability, and eventual amputation. With the prolongation of the
1.Introduction Mitochondria, a type of highly plastic organelle, can maintain a relatively stable dynamic equilibrium state towards the morphology, structure, quantity, volume, quality, and function
1. Introduction Atherosclerosis is a chronic progressive inflammatory disease, which is featured by the accumulation of lipids in the intima of the arteries with yellow appearance. This disease
1. Introduction Mitochondria are the center of energy metabolism in cardiomyocytes, which are necessary for maintaining normal myocardial contractility and cardiac function. Typically, the de
1. Introduction According to the 2020 report of World Health Organization (WHO), there are approximately 2.3 million cases with breast cancer worldwide. Breast cancer has emerged as one of the
1.Introduction The senescence in mammals is generally concomitant with the dysregulation of intestinal homeostasis and the accumulation of mitochondrial DNA (mtDNA) mutations. High-burden mtDNA mutations lead to N
1. Introduction At present, vaccine is the preferred option for the prevention of foot-and-mouth disease (FMD), for which the adjuvant is essential due to its strong role in boosting immune response associated wi
1. Introduction Acute lung injury comprises a uniform response of the lung to inflammatory or chemical insults which is commonly caused by systemic illness including sepsis or trauma, infection with pathogens, and tox
1. Introduction Gastric cancer (GC) represents a global health-care challenge, which is the fifth most common cancer and the fourth leading cause of cancer death across the world in 2020, with a significant
1. Introduction Supplementation of nicotinamide mononucleotide (NMN) to upregulate the level of nicotinamide adenine dinucleotide (NAD+) has been unveiled to be a promising anti-aging intervention. However, it is
1.Introduction Nicotinamide adenine dinucleotide phosphate hydrogen (NADPH), also known as reduced coenzyme II, is a critical cofactor in cellular antioxidant systems and lipid synthesis, which links insulin
1. Introduction Dengue fever is an acute infectious disease caused by the Dengue virus through the bite of an infected Aedes species (Ae. aegypti or Ae. albopictus) mosquito, with the main symptoms such as hi
1. Introduction The NAD precursor nicotinamide mononucleotide (NMN) shows a beneficial effect on ageing, yet excessive NMN accumulation may lead to axon degeneration. How to make the anti-ageing
1 Introduction Nicotinamide riboside (NR), a derivative of vitamin B3, is a new type of bioactive substance, which can be generated by binding a carbohydrate molecular ribose with nicotinamide (a
1. Introduction Heart failure is a serious condition in the development of cardiovascular disease. In particular, diastolic heart failure, as one of the most common manifestations of heart failure in
1. Introduction Ginseng has always been highly perceived as a valuable traditional Chinese medicine in China. Currently, much attention also has been paid to ginsenosides, the main active ingredients extracted from g
1. Introduction On July 2023, the World Health Organization (WHO) has classified the soda sweetener aspartame as a possible carcinogen, but said that aspartame is safe to consume with
Myocardial mitochondria are primary sites of myocardial energy metabolism. Mitochondrial disorders are associated with various cardiac diseases. Mitochondrial translation defects cause not only mitochondrial
The inflammation reaction and disruption of the skin barrier caused by oxidative stress play a crucial role in the process of Atopic Dermatitis (AD). Lipid peroxidation levels are often higher in AD patients, while antio
Vitamin D and B3 (niacin) could aid immune activation and CD4+ T cell reconstitution in INRs. NAD, vital for cellular function, declines with age, linking to various diseases. NAD boosters like NMN, NR, and NAM show prom
Sepsis, marked by dysregulated infection response, lacks effective treatment. NAD+'s role in inflammation remains unclear. NAD+ transport challenges limit its therapeutic impact. Novel NAD+-loaded nanoparticles (NPs)
In clinical diagnostics, enzymes are important biocatalysts and they play a key role in many biochemical reactions. These enzymes require coenzymes, what we call Diagnostic Reagent Coenzymes, to perform their functions.
The blood-brain barrier (BBB) is a critical component of the central nervous system that regulates the exchange of molecules between the brain and the bloodstream. Age-related changes in the BBB can lead to increased per
Vascular dementia is one of the serious and irreversible syndromes of acquired intelligence impairment caused by a series of cerebrovascular diseases. Citicoline is the derivative of nucleo- side, which can not only exhi
In the quest for a healthier lifestyle, the sweetener debate continues to rage. While sugar has long been the default choice, its adverse health effects have prompted a search for alternatives. One such swe
The nicotinamide adenine dinucleotide (NAD+ )/reduced NAD+ (NADH) and NADP+/reduced NADP+ (NADPH) redox couples are essential for maintaining cellular redox homeostasis and for modulating numerous biologic
Hypertension is a major global health concern, linked to millions of deaths due to cardiovascular issues. It involves endothelial dysfunction and arterial stiffness, contributing to atherosclerotic diseases. Improving va
High-sugar diets have led to a rising prevalence of various chronic illnesses, including obesity, diabetes, cardiovascular diseases, and hypertension, posing a significant global public health concern. Stevia Rebaudiosid
CFS is a disorder of unknown etiology, consisting of prolonged, debilitating fatigue, and a multitude of symptoms including neurocognitive dysfunction, flu-like symptoms, myalgia, weakness, arthralgia, low-grade fev
Alcohol is a kind of psychoactive substance, which has been commonly used in several cultures for centuries. Alcohol intake is the main cause of acute liver injury and chronic liver disease. Alcoholism can accelerate man
Stevia (Stevia rebaudiana Bertoni), a perennial shrub of the Compositae family, is cultivated in many regions across the world. It is famous for its sweetness, which is due to the presence of steviol glycosides, having 1
Stevioside is a natural sweetener derived from the stevia plant. It has a high sweetness intensity and low-calorie content, making it attractive for diabetics and others on carbohydrate-controlled diets. However, stevios
Highlight: In chronic HBV infection elevated ROS production is associated to high DNA damage in HBV-specific CD8 T cells - Response to DNA damage is dysfunctional - Up-regulation of CD38 and persistent activatio
In the pass decades days, the Open AI and the amazing founder behind AI application both captured attention world widely. But recently, as MIT Technology Review reported, the OpenAI CEO Sam Altman has turned ou
NMNH Potently Enhances NAD+ and Suppresses Glycolysis, the TCA Cycle, and Cell Growth NAD+ is essential for biological processes such as metabolism and DNA repair, and its decline is associated with age-related diseas
Ginsenosides on Cancer and Related Clinical Studies Cancer is a leading cause of death globally, and its treatment often involves a combination of surgery, chemotherapy, and radiation therapy. These treatm
Growth-coupled enzyme engineering through manipulation of redox cofactor regeneration An increasingly wide range of chemicals are now being produced from renewable feedstocks through biotechnological means. Biopro
Supervision Policies for NMN in Japan, China, America, Australia and Canada The mainstream researches of NMN have been conducted since a decade years ago. The United States had already carried out its commerciali
Collections of Clinical Trails on NMN Oral Administation NMN, as one of NAD+ booster family critical members, become increasingly popular on the market in the filed of health pomoting. And to date, there are
With the epidemic control policies loosening worldwide, residents in China, India, Malaysia, Japan and Singapore have suffered a shortage of medicines to varying degrees. But on the other hand, the type of medicines av
Attention! The Cambridge University Researchers Found Ursodeoxycholic Acid (UDCA) Can Prevent and Treat Covid-19 The International academic journal Nature published an article titled FXR inhibition may protect from SARS
On August 10, 2021, researchers from Shanghai University of Science and Technology published an article titled NAD+ supplement potentiates tumor killing function by rescuing defective TUBBY-mediated NAMPT transcrip
